Entity Details

Primary name GLUT4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP14672
EntryNameGLUT4_HUMAN
FullNameSolute carrier family 2, facilitated glucose transporter member 4
TaxID9606
Evidenceevidence at protein level
Length509
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesSLC2A4

GO terms

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GOName
GO:0005355 glucose transmembrane transporter activity
GO:0005771 multivesicular body
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005905 clathrin-coated pit
GO:0005975 carbohydrate metabolic process
GO:0007611 learning or memory
GO:0007614 short-term memory
GO:0007616 long-term memory
GO:0009897 external side of plasma membrane
GO:0010021 amylopectin biosynthetic process
GO:0012505 endomembrane system
GO:0012506 vesicle membrane
GO:0016020 membrane
GO:0016529 sarcoplasmic reticulum
GO:0030136 clathrin-coated vesicle
GO:0030140 trans-Golgi network transport vesicle
GO:0030315 T-tubule
GO:0030659 cytoplasmic vesicle membrane
GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway
GO:0032593 insulin-responsive compartment
GO:0032869 cellular response to insulin stimulus
GO:0042383 sarcolemma
GO:0042593 glucose homeostasis
GO:0044381 glucose import in response to insulin stimulus
GO:0045121 membrane raft
GO:0045471 response to ethanol
GO:0046323 glucose import
GO:0048471 perinuclear region of cytoplasm
GO:0050873 brown fat cell differentiation
GO:0055056 D-glucose transmembrane transporter activity
GO:0070062 extracellular exosome
GO:0071356 cellular response to tumor necrosis factor
GO:0071456 cellular response to hypoxia
GO:0071470 cellular response to osmotic stress
GO:0098694 regulation of synaptic vesicle budding from presynaptic endocytic zone membrane
GO:0098793 presynapse
GO:0150104 transport across blood-brain barrier
GO:1904659 glucose transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Endomembrane system

Domains

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DomainNameCategoryType
IPR002441 Glucose transporter, type 4 (GLUT4)FamilyFamily
IPR003663 Sugar/inositol transporterFamilyFamily
IPR005828 Major facilitator, sugar transporter-likeFamilyFamily
IPR005829 Sugar transporter, conserved siteSiteConserved site
IPR020846 Major facilitator superfamily domainDomainDomain
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00126 Ascorbic acidDrugbanksmall molecule
DB01914 D-glucoseSwissprotsmall molecule
DB09341 Dextrose, unspecified formSwissprotsmall molecule
DB09502 Fludeoxyglucose (18F)Swissprotsmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GLUT4_HUMANUBC9_MOUSEBioGRID10655495 details