Entity Details

Primary name ETS1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP14921
EntryNameETS1_HUMAN
FullNameProtein C-ets-1
TaxID9606
Evidenceevidence at protein level
Length441
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesETS1

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001666 response to hypoxia
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0006955 immune response
GO:0007565 female pregnancy
GO:0008134 transcription factor binding
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0009612 response to mechanical stimulus
GO:0010595 positive regulation of endothelial cell migration
GO:0010628 positive regulation of gene expression
GO:0010715 regulation of extracellular matrix disassembly
GO:0021854 hypothalamus development
GO:0021983 pituitary gland development
GO:0030154 cell differentiation
GO:0030374 nuclear receptor coactivator activity
GO:0030578 PML body organization
GO:0032355 response to estradiol
GO:0034616 response to laminar fluid shear stress
GO:0035035 histone acetyltransferase binding
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0044849 estrous cycle
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045765 regulation of angiogenesis
GO:0045766 positive regulation of angiogenesis
GO:0045786 negative regulation of cell cycle
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046677 response to antibiotic
GO:0048870 cell motility
GO:0050729 positive regulation of inflammatory response
GO:0051272 positive regulation of cellular component movement
GO:0060055 angiogenesis involved in wound healing
GO:0070301 cellular response to hydrogen peroxide
GO:0070555 response to interleukin-1
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000418 Ets domainDomainDomain
IPR003118 Pointed domainDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR016311 Transforming protein C-etsFamilyFamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR041886 Protein C-ets-1, pointed domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ETS1_HUMANGFI1_MOUSEUniProt17213822 details