Entity Details

Primary name ITA8_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionA2ARA8
EntryNameITA8_MOUSE
FullNameIntegrin alpha-8
TaxID10090
Evidenceevidence at protein level
Length1062
SequenceStatuscomplete
DateCreated2007-08-21
DateModified2021-06-02

Ontological Relatives

GenesItga8

GO terms

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GOName
GO:0001656 metanephros development
GO:0001822 kidney development
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0007420 brain development
GO:0007613 memory
GO:0008305 integrin complex
GO:0009986 cell surface
GO:0014069 postsynaptic density
GO:0030030 cell projection organization
GO:0030198 extracellular matrix organization
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0032591 dendritic spine membrane
GO:0034446 substrate adhesion-dependent cell spreading
GO:0042472 inner ear morphogenesis
GO:0043204 perikaryon
GO:0045177 apical part of cell
GO:0045184 establishment of protein localization
GO:0046872 metal ion binding
GO:0048745 smooth muscle tissue development
GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation

Subcellular Location

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Subcellular Location
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR000413 Integrin alpha chainFamilyFamily
IPR013517 FG-GAP repeatRepeatRepeat
IPR013519 Integrin alpha beta-propellorRepeatRepeat
IPR013649 Integrin alpha-2DomainDomain
IPR018184 Integrin alpha chain, C-terminal cytoplasmic region, conserved siteSiteConserved site
IPR028994 Integrin alpha, N-terminalFamilyHomologous superfamily
IPR032695 Integrin domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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