Entity Details

Primary name HXA5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP09021
EntryNameHXA5_MOUSE
FullNameHomeobox protein Hox-A5
TaxID10090
Evidenceevidence at protein level
Length270
SequenceStatuscomplete
DateCreated1988-11-01
DateModified2021-06-02

Ontological Relatives

GenesHoxa5

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001501 skeletal system development
GO:0002009 morphogenesis of an epithelium
GO:0003016 respiratory system process
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007389 pattern specification process
GO:0007585 respiratory gaseous exchange by respiratory system
GO:0009952 anterior/posterior pattern specification
GO:0010628 positive regulation of gene expression
GO:0016477 cell migration
GO:0016525 negative regulation of angiogenesis
GO:0030324 lung development
GO:0030878 thyroid gland development
GO:0033599 regulation of mammary gland epithelial cell proliferation
GO:0035264 multicellular organism growth
GO:0043065 positive regulation of apoptotic process
GO:0045639 positive regulation of myeloid cell differentiation
GO:0045647 negative regulation of erythrocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048286 lung alveolus development
GO:0048704 embryonic skeletal system morphogenesis
GO:0048706 embryonic skeletal system development
GO:0060435 bronchiole development
GO:0060439 trachea morphogenesis
GO:0060441 epithelial tube branching involved in lung morphogenesis
GO:0060480 lung goblet cell differentiation
GO:0060481 lobar bronchus epithelium development
GO:0060484 lung-associated mesenchyme development
GO:0060535 trachea cartilage morphogenesis
GO:0060536 cartilage morphogenesis
GO:0060574 intestinal epithelial cell maturation
GO:0060638 mesenchymal-epithelial cell signaling
GO:0060644 mammary gland epithelial cell differentiation
GO:0060749 mammary gland alveolus development
GO:0060764 cell-cell signaling involved in mammary gland development
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR001827 Homeobox protein, antennapedia type, conserved siteSiteConserved site
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR017995 Homeobox protein, antennapedia typeFamilyFamily
IPR020479 Homeobox domain, metazoaDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
HXA5_MOUSEMEIS1_MOUSEIntAct15617687 20211142 details
HXA5_MOUSEPBX1_MOUSEBioGRID, IntAct20211142 details