Entity Details

Primary name CHIN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15882
EntryNameCHIN_HUMAN
FullNameN-chimaerin
TaxID9606
Evidenceevidence at protein level
Length459
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesCHN1

GO terms

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GOName
GO:0005096 GTPase activator activity
GO:0005829 cytosol
GO:0008045 motor neuron axon guidance
GO:0035556 intracellular signal transduction
GO:0043087 regulation of GTPase activity
GO:0046872 metal ion binding
GO:0046875 ephrin receptor binding
GO:0048013 ephrin receptor signaling pathway
GO:0050770 regulation of axonogenesis
GO:0051056 regulation of small GTPase mediated signal transduction

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR000980 SH2 domainDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR017356 ChimaerinFamilyFamily
IPR020454 Diacylglycerol/phorbol-ester bindingDomainDomain
IPR035840 Chimaerin, SH2 domainDomainDomain
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily
IPR037860 Chimaerin, RhoGAP domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CHIN_HUMANNMDE1_MOUSEBioGRID16221859 details
CHIN_HUMANEPHA4_MOUSEDIP17911252 details