Entity Details

Primary name ITF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15884
EntryNameITF2_HUMAN
FullNameTranscription factor 4
TaxID9606
Evidenceevidence at protein level
Length667
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesTCF4

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001093 TFIIB-class transcription factor binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0008013 beta-catenin binding
GO:0008022 protein C-terminus binding
GO:0030154 cell differentiation
GO:0042802 identical protein binding
GO:0045666 positive regulation of neuron differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0065004 protein-DNA complex assembly
GO:0070369 beta-catenin-TCF7L2 complex
GO:0070888 E-box binding
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990907 beta-catenin-TCF complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions