Entity Details

Primary name TFE2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15923
EntryNameTFE2_HUMAN
FullNameTranscription factor E2-alpha
TaxID9606
Evidenceevidence at protein level
Length654
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesTCF3

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000791 euchromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002326 B cell lineage commitment
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0008134 transcription factor binding
GO:0030183 B cell differentiation
GO:0030890 positive regulation of B cell proliferation
GO:0031435 mitogen-activated protein kinase kinase kinase binding
GO:0032991 protein-containing complex
GO:0033152 immunoglobulin V(D)J recombination
GO:0042803 protein homodimerization activity
GO:0043425 bHLH transcription factor binding
GO:0045666 positive regulation of neuron differentiation
GO:0045787 positive regulation of cell cycle
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051149 positive regulation of muscle cell differentiation
GO:0070644 vitamin D response element binding
GO:0070888 E-box binding
GO:0090575 RNA polymerase II transcription regulator complex
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:2000045 regulation of G1/S transition of mitotic cell cycle

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table