Entity Details

Primary name RFA2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15927
EntryNameRFA2_HUMAN
FullNameReplication protein A 32 kDa subunit
TaxID9606
Evidenceevidence at protein level
Length270
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesRPA2

GO terms

Show/Hide Table
GOName
GO:0000723 telomere maintenance
GO:0000724 double-strand break repair via homologous recombination
GO:0000781 chromosome, telomeric region
GO:0000785 chromatin
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005662 DNA replication factor A complex
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006284 base-excision repair
GO:0006287 base-excision repair, gap-filling
GO:0006289 nucleotide-excision repair
GO:0006293 nucleotide-excision repair, preincision complex stabilization
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0006298 mismatch repair
GO:0010569 regulation of double-strand break repair via homologous recombination
GO:0016604 nuclear body
GO:0016605 PML body
GO:0019899 enzyme binding
GO:0019903 protein phosphatase binding
GO:0019985 translesion synthesis
GO:0031571 mitotic G1 DNA damage checkpoint signaling
GO:0031625 ubiquitin protein ligase binding
GO:0032201 telomere maintenance via semi-conservative replication
GO:0033683 nucleotide-excision repair, DNA incision
GO:0034502 protein localization to chromosome
GO:0036297 interstrand cross-link repair
GO:0042276 error-prone translesion synthesis
GO:0042769 DNA damage response, detection of DNA damage
GO:0047485 protein N-terminus binding
GO:0070987 error-free translesion synthesis
GO:0098505 G-rich strand telomeric DNA binding
GO:1900034 regulation of cellular response to heat
GO:1901796 regulation of signal transduction by p53 class mediator
GO:2000001 regulation of DNA damage checkpoint

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR014646 Replication factor A protein 2FamilyFamily
IPR014892 Replication protein A, C-terminalDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR040260 Replication factor A protein-likeFamilyFamily

Diseases

Show/Hide Table

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink