Entity Details

Primary name MUC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15941
EntryNameMUC1_HUMAN
FullNameMucin-1
TaxID9606
Evidenceevidence at protein level
Length1255
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesMUC1

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0002039 p53 binding
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0003712 transcription coregulator activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005796 Golgi lumen
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0016266 O-glycan processing
GO:0016324 apical plasma membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0031982 vesicle
GO:0033629 negative regulation of cell adhesion mediated by integrin
GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress
GO:0070062 extracellular exosome
GO:0090240 positive regulation of histone H4 acetylation
GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane
Cytoplasm
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR000082 SEA domainDomainDomain
IPR036364 SEA domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB06584 TG4010Drugbankbiotech
DB11090 Potassium nitrateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
MUC1_HUMANCTNB1_MOUSEBioGRID15221004 details