Entity Details

Primary name CD44_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP16070
EntryNameCD44_HUMAN
FullNameCD44 antigen
TaxID9606
Evidenceevidence at protein level
Length742
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesCD44

GO terms

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GOName
GO:0004888 transmembrane signaling receptor activity
GO:0005518 collagen binding
GO:0005540 hyaluronic acid binding
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005902 microvillus
GO:0005925 focal adhesion
GO:0006954 inflammatory response
GO:0007155 cell adhesion
GO:0007160 cell-matrix adhesion
GO:0009986 cell surface
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016477 cell migration
GO:0022617 extracellular matrix disassembly
GO:0030198 extracellular matrix organization
GO:0030214 hyaluronan catabolic process
GO:0030667 secretory granule membrane
GO:0031258 lamellipodium membrane
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034116 positive regulation of heterotypic cell-cell adhesion
GO:0035692 macrophage migration inhibitory factor receptor complex
GO:0042110 T cell activation
GO:0042995 cell projection
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043312 neutrophil degranulation
GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0044319 wound healing, spreading of cells
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050900 leukocyte migration
GO:0051216 cartilage development
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0070062 extracellular exosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070487 monocyte aggregation
GO:0098609 cell-cell adhesion
GO:1900625 positive regulation of monocyte aggregation
GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2000392 regulation of lamellipodium morphogenesis

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000538 Link domainDomainDomain
IPR001231 CD44 antigenFamilyFamily
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR043210 CD44 antigen-likeFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB06550 BivatuzumabDrugbankbiotech
DB08818 Hyaluronic acidDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink