Entity Details

Primary name ITB4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP16144
EntryNameITB4_HUMAN
FullNameIntegrin beta-4
TaxID9606
Evidenceevidence at protein level
Length1822
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesITGB4

GO terms

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GOName
GO:0001664 G protein-coupled receptor binding
GO:0005178 integrin binding
GO:0005604 basement membrane
GO:0005730 nucleolus
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006914 autophagy
GO:0007155 cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0008305 integrin complex
GO:0009611 response to wounding
GO:0009925 basal plasma membrane
GO:0009986 cell surface
GO:0016477 cell migration
GO:0030054 cell junction
GO:0030056 hemidesmosome
GO:0030198 extracellular matrix organization
GO:0030199 collagen fibril organization
GO:0031252 cell leading edge
GO:0031581 hemidesmosome assembly
GO:0031965 nuclear membrane
GO:0032290 peripheral nervous system myelin formation
GO:0033627 cell adhesion mediated by integrin
GO:0035878 nail development
GO:0043235 receptor complex
GO:0043589 skin morphogenesis
GO:0046847 filopodium assembly
GO:0048333 mesodermal cell differentiation
GO:0048870 cell motility
GO:0061450 trophoblast cell migration
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR002369 Integrin beta subunit, VWA domainDomainDomain
IPR003644 Na-Ca exchanger/integrin-beta4DomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR012013 Integrin beta-4 subunitFamilyFamily
IPR012896 Integrin beta subunit, tailDomainDomain
IPR013111 EGF-like domain, extracellularDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015812 Integrin beta subunitFamilyFamily
IPR016201 PSI domainDomainDomain
IPR033760 Integrin beta N-terminalDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036349 Integrin beta tail domain superfamilyFamilyHomologous superfamily
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily
IPR038081 CalX-like domain superfamilyFamilyHomologous superfamily
IPR040622 Integrin beta, epidermal growth factor-like domain 1DomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB05122 R1295Drugbanksmall molecule