Entity Details

Primary name HXC8_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP09025
EntryNameHXC8_MOUSE
FullNameHomeobox protein Hox-C8
TaxID10090
Evidenceevidence at protein level
Length242
SequenceStatuscomplete
DateCreated1988-11-01
DateModified2021-06-02

Ontological Relatives

GenesHoxc8

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0009952 anterior/posterior pattern specification
GO:0015630 microtubule cytoskeleton
GO:0030182 neuron differentiation
GO:0048705 skeletal system morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000047 Helix-turn-helix motifSiteConserved site
IPR001356 Homeobox domainDomainDomain
IPR001827 Homeobox protein, antennapedia type, conserved siteSiteConserved site
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
HXC8_MOUSEGEMI_MOUSEBioGRID, IntAct14973489 details
HXC8_MOUSEJUN_MOUSEBioGRID11551904 details