Entity Details

Primary name TCPA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17987
EntryNameTCPA_HUMAN
FullNameT-complex protein 1 subunit alpha
TaxID9606
Evidenceevidence at protein level
Length556
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesTCP1

GO terms

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GOName
GO:0000242 pericentriolar material
GO:0000792 heterochromatin
GO:0001669 acrosomal vesicle
GO:0002199 zona pellucida receptor complex
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005832 chaperonin-containing T-complex
GO:0005874 microtubule
GO:0006457 protein folding
GO:0007021 tubulin complex assembly
GO:0007339 binding of sperm to zona pellucida
GO:0016887 ATP hydrolysis activity
GO:0031625 ubiquitin protein ligase binding
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0035722 interleukin-12-mediated signaling pathway
GO:0044053 translocation of peptides or proteins into host cell cytoplasm
GO:0044183 protein folding chaperone
GO:0044297 cell body
GO:0050821 protein stabilization
GO:0051082 unfolded protein binding
GO:0051973 positive regulation of telomerase activity
GO:0070062 extracellular exosome
GO:0090666 scaRNA localization to Cajal body
GO:1901998 toxin transport
GO:1904851 positive regulation of establishment of protein localization to telomere
GO:1904871 positive regulation of protein localization to Cajal body
GO:1904874 positive regulation of telomerase RNA localization to Cajal body
GO:2000109 regulation of macrophage apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002194 Chaperonin TCP-1, conserved siteSiteConserved site
IPR002423 Chaperonin Cpn60/TCP-1 familyFamilyFamily
IPR012715 T-complex protein 1, alpha subunitFamilyFamily
IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)FamilyFamily
IPR027409 GroEL-like apical domain superfamilyFamilyHomologous superfamily
IPR027410 TCP-1-like chaperonin intermediate domain superfamilyFamilyHomologous superfamily
IPR027413 GroEL-like equatorial domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TCPA_HUMANOSTM1_MOUSEBioGRID26598607 details