Entity Details

Primary name ITB5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP18084
EntryNameITB5_HUMAN
FullNameIntegrin beta-5
TaxID9606
Evidenceevidence at protein level
Length799
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesITGB5

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005178 integrin binding
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006936 muscle contraction
GO:0007160 cell-matrix adhesion
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0009986 cell surface
GO:0016477 cell migration
GO:0030198 extracellular matrix organization
GO:0033627 cell adhesion mediated by integrin
GO:0034684 integrin alphav-beta5 complex
GO:0035987 endodermal cell differentiation
GO:0038023 signaling receptor activity
GO:0043149 stress fiber assembly
GO:0043235 receptor complex
GO:0045335 phagocytic vesicle
GO:0070062 extracellular exosome
GO:0090136 epithelial cell-cell adhesion

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR002035 von Willebrand factor, type ADomainDomain
IPR002369 Integrin beta subunit, VWA domainDomainDomain
IPR012896 Integrin beta subunit, tailDomainDomain
IPR014836 Integrin beta subunit, cytoplasmic domainDomainDomain
IPR015812 Integrin beta subunitFamilyFamily
IPR016201 PSI domainDomainDomain
IPR027067 Integrin beta-5 subunitFamilyFamily
IPR032695 Integrin domain superfamilyFamilyHomologous superfamily
IPR033760 Integrin beta N-terminalDomainDomain
IPR036349 Integrin beta tail domain superfamilyFamilyHomologous superfamily
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily
IPR040622 Integrin beta, epidermal growth factor-like domain 1DomainDomain

Diseases

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