Entity Details

Primary name VINC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP18206
EntryNameVINC_HUMAN
FullNameVinculin
TaxID9606
Evidenceevidence at protein level
Length1134
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesVCL

GO terms

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GOName
GO:0002009 morphogenesis of an epithelium
GO:0002102 podosome
GO:0002162 dystroglycan binding
GO:0002576 platelet degranulation
GO:0003779 actin binding
GO:0005198 structural molecule activity
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005903 brush border
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005915 zonula adherens
GO:0005916 fascia adherens
GO:0005925 focal adhesion
GO:0006936 muscle contraction
GO:0007155 cell adhesion
GO:0007160 cell-matrix adhesion
GO:0008013 beta-catenin binding
GO:0030032 lamellipodium assembly
GO:0030055 cell-substrate junction
GO:0030336 negative regulation of cell migration
GO:0031625 ubiquitin protein ligase binding
GO:0032991 protein-containing complex
GO:0034333 adherens junction assembly
GO:0034394 protein localization to cell surface
GO:0034774 secretory granule lumen
GO:0035580 specific granule lumen
GO:0035633 maintenance of blood-brain barrier
GO:0042383 sarcolemma
GO:0043034 costamere
GO:0043297 apical junction assembly
GO:0043312 neutrophil degranulation
GO:0044291 cell-cell contact zone
GO:0045121 membrane raft
GO:0045294 alpha-catenin binding
GO:0045296 cadherin binding
GO:0048675 axon extension
GO:0051893 regulation of focal adhesion assembly
GO:0070062 extracellular exosome
GO:0070527 platelet aggregation
GO:0090136 epithelial cell-cell adhesion
GO:0090636 outer dense plaque of desmosome
GO:0090637 inner dense plaque of desmosome
GO:1903140 regulation of establishment of endothelial barrier
GO:1903561 extracellular vesicle
GO:1904702 regulation of protein localization to adherens junction
GO:1904813 ficolin-1-rich granule lumen
GO:1990357 terminal web

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000633 Vinculin, conserved siteSiteConserved site
IPR006077 Vinculin/alpha-cateninFamilyFamily
IPR017997 VinculinFamilyFamily
IPR036723 Alpha-catenin/vinculin-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
VINC_HUMANRAVR1_MOUSEBioGRID11724819 details
VINC_HUMANSRBS1_MOUSEMINT17082770 details