Entity Details

Primary name EPOR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP19235
EntryNameEPOR_HUMAN
FullNameErythropoietin receptor
TaxID9606
Evidenceevidence at protein level
Length508
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesEPOR

GO terms

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GOName
GO:0004900 erythropoietin receptor activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0007420 brain development
GO:0007507 heart development
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016607 nuclear speck
GO:0042802 identical protein binding
GO:0046579 positive regulation of Ras protein signal transduction
GO:0046697 decidualization

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR003528 Long hematopoietin receptor, single chain, conserved siteSiteConserved site
IPR003961 Fibronectin type IIIDomainDomain
IPR009167 Erythropoietin receptorFamilyFamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015152 Growth hormone/erythropoietin receptor, ligand bindingDomainDomain
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00012 Darbepoetin alfaDrugbankbiotech
DB00016 ErythropoietinDrugbankbiotech
DB07637 DibromotyrosineDrugbanksmall molecule
DB08894 PeginesatideDrugbankbiotech
DB09107 Methoxy polyethylene glycol-epoetin betaDrugbankbiotech