Entity Details

Primary name RPAB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP19388
EntryNameRPAB1_HUMAN
FullNameDNA-directed RNA polymerases I, II, and III subunit RPABC1
TaxID9606
Evidenceevidence at protein level
Length210
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesPOLR2E

GO terms

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GOName
GO:0000398 mRNA splicing, via spliceosome
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0005666 RNA polymerase III complex
GO:0005736 RNA polymerase I complex
GO:0005829 cytosol
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006351 transcription, DNA-templated
GO:0006361 transcription initiation from RNA polymerase I promoter
GO:0006363 termination of RNA polymerase I transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006370 7-methylguanosine mRNA capping
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0016032 viral process
GO:0016070 RNA metabolic process
GO:0032481 positive regulation of type I interferon production
GO:0042795 snRNA transcription by RNA polymerase II
GO:0045815 positive regulation of gene expression, epigenetic
GO:0048239 negative regulation of DNA recombination at telomere
GO:0050434 positive regulation of viral transcription
GO:0060964 regulation of gene silencing by miRNA

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000783 RNA polymerase, subunit H/Rpb5 C-terminalDomainDomain
IPR005571 RNA polymerase, Rpb5, N-terminalDomainDomain
IPR014381 DNA-directed RNA polymerase RPB5 subunit, eukaryote/virusFamilyFamily
IPR020608 RNA polymerase, subunit H/Rpb5, conserved siteSiteConserved site
IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunitFamilyFamily
IPR035913 RPB5-like RNA polymerase subunit superfamilyFamilyHomologous superfamily
IPR036710 RNA polymerase Rpb5, N-terminal domain superfamilyFamilyHomologous superfamily
IPR039531 DNA-directed RNA polymerase subunit Rpb5-likeFamilyFamily

Diseases

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Interactions

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