Entity Details

Primary name NUCL_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP09405
EntryNameNUCL_MOUSE
FullNameNucleolin
TaxID10090
Evidenceevidence at protein level
Length707
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesNcl

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001650 fibrillar center
GO:0001651 dense fibrillar component
GO:0003697 single-stranded DNA binding
GO:0003723 RNA binding
GO:0005102 signaling receptor binding
GO:0005509 calcium ion binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005938 cell cortex
GO:0006897 endocytosis
GO:0008022 protein C-terminus binding
GO:0009986 cell surface
GO:0017148 negative regulation of translation
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035368 selenocysteine insertion sequence binding
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0042134 rRNA primary transcript binding
GO:0042162 telomeric DNA binding
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043236 laminin binding
GO:0043565 sequence-specific DNA binding
GO:0044547 DNA topoisomerase binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048026 positive regulation of mRNA splicing, via spliceosome
GO:0048027 mRNA 5'-UTR binding
GO:0071222 cellular response to lipopolysaccharide
GO:0071364 cellular response to epidermal growth factor stimulus
GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
GO:1990631 ErbB-4 class receptor binding
GO:1990830 cellular response to leukemia inhibitory factor
GO:1990904 ribonucleoprotein complex
GO:2000232 regulation of rRNA processing

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034230 Nucleolin, RNA recognition motif 1DomainDomain
IPR034233 Nucleolin, RNA recognition motif 2DomainDomain
IPR034234 Nucleolin, RNA recognition motif 3DomainDomain
IPR034235 Nucleolin, RNA recognition motif 4DomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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