Entity Details

Primary name CSK22_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP19784
EntryNameCSK22_HUMAN
FullNameCasein kinase II subunit alpha'
TaxID9606
Evidenceevidence at protein level
Length350
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesCSNK2A2

GO terms

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GOName
GO:0000785 chromatin
GO:0001669 acrosomal vesicle
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005956 protein kinase CK2 complex
GO:0006457 protein folding
GO:0006656 phosphatidylcholine biosynthetic process
GO:0006915 apoptotic process
GO:0007076 mitotic chromosome condensation
GO:0007283 spermatogenesis
GO:0016055 Wnt signaling pathway
GO:0016236 macroautophagy
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0021987 cerebral cortex development
GO:0047485 protein N-terminus binding
GO:0051726 regulation of cell cycle
GO:0097421 liver regeneration
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1903146 regulation of autophagy of mitochondrion
GO:1903955 positive regulation of protein targeting to mitochondrion
GO:1905818 regulation of chromosome separation
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process
GO:2001234 negative regulation of apoptotic signaling pathway

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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Drugs

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DrugNameSourceType
DB07546 [1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acidDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule