Entity Details

Primary name IGF2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP09535
EntryNameIGF2_MOUSE
FullNameInsulin-like growth factor II
TaxID10090
Evidenceevidence at protein level
Length180
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesIgf2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001649 osteoblast differentiation
GO:0001701 in utero embryonic development
GO:0001892 embryonic placenta development
GO:0001934 positive regulation of protein phosphorylation
GO:0005158 insulin receptor binding
GO:0005159 insulin-like growth factor receptor binding
GO:0005178 integrin binding
GO:0005179 hormone activity
GO:0005615 extracellular space
GO:0006006 glucose metabolic process
GO:0007613 memory
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0009887 animal organ morphogenesis
GO:0014070 response to organic cyclic compound
GO:0031017 exocrine pancreas development
GO:0031056 regulation of histone modification
GO:0035094 response to nicotine
GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase
GO:0040018 positive regulation of multicellular organism growth
GO:0042104 positive regulation of activated T cell proliferation
GO:0042493 response to drug
GO:0043085 positive regulation of catalytic activity
GO:0043410 positive regulation of MAPK cascade
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0043539 protein serine/threonine kinase activator activity
GO:0045725 positive regulation of glycogen biosynthetic process
GO:0045766 positive regulation of angiogenesis
GO:0045840 positive regulation of mitotic nuclear division
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity
GO:0046622 positive regulation of organ growth
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0048018 receptor ligand activity
GO:0048633 positive regulation of skeletal muscle tissue growth
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051146 striated muscle cell differentiation
GO:0051147 regulation of muscle cell differentiation
GO:0051148 negative regulation of muscle cell differentiation
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling
GO:0060669 embryonic placenta morphogenesis
GO:0060720 spongiotrophoblast cell proliferation
GO:0062023 collagen-containing extracellular matrix
GO:0090031 positive regulation of steroid hormone biosynthetic process
GO:1905564 positive regulation of vascular endothelial cell proliferation
GO:2000467 positive regulation of glycogen (starch) synthase activity

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR013576 Insulin-like growth factor II E-peptide, C-terminalDomainDomain
IPR016179 Insulin-likeDomainDomain
IPR022334 Insulin-like growth factor IIFamilyFamily
IPR022350 Insulin-like growth factorFamilyFamily
IPR022352 Insulin familyFamilyFamily
IPR022353 Insulin, conserved siteSiteConserved site
IPR036438 Insulin-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
IGF2_MOUSEIBP3_HUMANBioGRID12962157 details
IGF2_MOUSEMYORG_MOUSEBioGRID19706595 details