Entity Details

Primary name VDAC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP21796
EntryNameVDAC1_HUMAN
FullNameVoltage-dependent anion-selective channel protein 1
TaxID9606
Evidenceevidence at protein level
Length283
SequenceStatuscomplete
DateCreated1991-05-01
DateModified2021-06-02

Ontological Relatives

GenesVDAC1

GO terms

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GOName
GO:0001662 behavioral fear response
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005757 mitochondrial permeability transition pore complex
GO:0005886 plasma membrane
GO:0006090 pyruvate metabolic process
GO:0006820 anion transport
GO:0006851 mitochondrial calcium ion transmembrane transport
GO:0006915 apoptotic process
GO:0007270 neuron-neuron synaptic transmission
GO:0007612 learning
GO:0008021 synaptic vesicle
GO:0008308 voltage-gated anion channel activity
GO:0015288 porin activity
GO:0015485 cholesterol binding
GO:0016020 membrane
GO:0016032 viral process
GO:0016236 macroautophagy
GO:0019901 protein kinase binding
GO:0030855 epithelial cell differentiation
GO:0031210 phosphatidylcholine binding
GO:0031966 mitochondrial membrane
GO:0042645 mitochondrial nucleoid
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0044325 transmembrane transporter binding
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0046930 pore complex
GO:0070062 extracellular exosome
GO:0097001 ceramide binding
GO:0110099 negative regulation of calcium import into the mitochondrion
GO:1901526 positive regulation of mitophagy
GO:1903146 regulation of autophagy of mitochondrion
GO:2000378 negative regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Cell membrane
Membrane raft
Mitochondrion outer membrane

Domains

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DomainNameCategoryType
IPR001925 Porin, eukaryotic typeFamilyFamily
IPR023614 Porin domain superfamilyFamilyHomologous superfamily
IPR027246 Eukaryotic porin/Tom40FamilyFamily
IPR030270 Voltage-dependent anion-selective channel protein 1FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01375 Aluminium monostearateDrugbanksmall molecule
DB09061 CannabidiolDrugbanksmall molecule
DB14009 Medical CannabisDrugbankbiotech
DB14011 NabiximolsDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink