Entity Details

Primary name FBRL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22087
EntryNameFBRL_HUMAN
FullNamerRNA 2'-O-methyltransferase fibrillarin
TaxID9606
Evidenceevidence at protein level
Length321
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesFBL

GO terms

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GOName
GO:0000494 box C/D RNA 3'-end processing
GO:0001094 TFIID-class transcription factor complex binding
GO:0001649 osteoblast differentiation
GO:0001650 fibrillar center
GO:0001651 dense fibrillar component
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0006364 rRNA processing
GO:0008649 rRNA methyltransferase activity
GO:0015030 Cajal body
GO:0016020 membrane
GO:0031167 rRNA methylation
GO:0031428 box C/D RNP complex
GO:0032040 small-subunit processome
GO:0048254 snoRNA localization
GO:0051117 ATPase binding
GO:0070062 extracellular exosome
GO:1990258 histone glutamine methylation
GO:1990259 histone-glutamine methyltransferase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000692 FibrillarinFamilyFamily
IPR020813 Fibrillarin, conserved siteSiteConserved site
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
FBRL_HUMANANM3_MOUSEI2D21242974 details
FBRL_HUMANANM1_MOUSEI2D21242974 details