Entity Details

Primary name CTLA4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP09793
EntryNameCTLA4_MOUSE
FullNameCytotoxic T-lymphocyte protein 4
TaxID10090
Evidenceevidence at protein level
Length223
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesCtla4

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0005794 Golgi apparatus
GO:0005887 integral component of plasma membrane
GO:0006974 cellular response to DNA damage stimulus
GO:0009897 external side of plasma membrane
GO:0030889 negative regulation of B cell proliferation
GO:0042130 negative regulation of T cell proliferation
GO:0043065 positive regulation of apoptotic process
GO:0045334 clathrin-coated endocytic vesicle
GO:0045590 negative regulation of regulatory T cell differentiation
GO:0048471 perinuclear region of cytoplasm
GO:0050777 negative regulation of immune response
GO:0050852 T cell receptor signaling pathway
GO:0050853 B cell receptor signaling pathway
GO:0098636 protein complex involved in cell adhesion

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR008096 Cytotoxic T-lymphocyte antigen 4FamilyFamily
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR040216 Cytotoxic T-lymphocyte protein 4/CD28FamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CTLA4_MOUSEAP2M1_MOUSEBioGRID9256472 details
CTLA4_MOUSEFYN_MOUSEMINT9712716 details