Entity Details

Primary name PUR6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22234
EntryNamePUR6_HUMAN
FullNameMultifunctional protein ADE2
TaxID9606
Evidenceevidence at protein level
Length425
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesPAICS

GO terms

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GOName
GO:0004638 phosphoribosylaminoimidazole carboxylase activity
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006189 'de novo' IMP biosynthetic process
GO:0009113 purine nucleobase biosynthetic process
GO:0009168 purine ribonucleoside monophosphate biosynthetic process
GO:0016020 membrane
GO:0042802 identical protein binding
GO:0043727 5-amino-4-imidazole carboxylate lyase activity
GO:0045296 cadherin binding
GO:0070062 extracellular exosome

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000031 PurE domainDomainDomain
IPR018236 SAICAR synthetase, conserved siteSiteConserved site
IPR028923 SAICAR synthetase/ADE2, N-terminalDomainDomain
IPR033626 Class II PurEDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00128 Aspartic acidDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PUR6_HUMANMK13_MOUSEBioGRID19135240 details