Entity Details

Primary name ROA2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22626
EntryNameROA2_HUMAN
FullNameHeterogeneous nuclear ribonucleoproteins A2/B1
TaxID9606
Evidenceevidence at protein level
Length353
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesHNRNPA2B1

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000398 mRNA splicing, via spliceosome
GO:0000781 chromosome, telomeric region
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0006397 mRNA processing
GO:0006406 mRNA export from nucleus
GO:0015030 Cajal body
GO:0016020 membrane
GO:0016032 viral process
GO:0016070 RNA metabolic process
GO:0016363 nuclear matrix
GO:0031053 primary miRNA processing
GO:0035198 miRNA binding
GO:0035722 interleukin-12-mediated signaling pathway
GO:0042802 identical protein binding
GO:0043047 single-stranded telomeric DNA binding
GO:0044806 G-quadruplex DNA unwinding
GO:0048025 negative regulation of mRNA splicing, via spliceosome
GO:0050658 RNA transport
GO:0070062 extracellular exosome
GO:0071013 catalytic step 2 spliceosome
GO:0097157 pre-mRNA intronic binding
GO:0098505 G-rich strand telomeric DNA binding
GO:1904358 positive regulation of telomere maintenance via telomere lengthening
GO:1905663 positive regulation of telomerase RNA reverse transcriptase activity
GO:1990247 N6-methyladenosine-containing RNA binding
GO:1990428 miRNA transport
GO:1990904 ribonucleoprotein complex

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Cytoplasmic granule
Nucleus
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034486 hnRNP A2/B1, RNA recognition motif 1DomainDomain
IPR034489 hnRNP A2/B1FamilyFamily
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB09130 CopperDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ROA2_HUMANPRIO_MOUSEIntAct16294306 details