Entity Details

Primary name KAPCB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22694
EntryNameKAPCB_HUMAN
FullNamecAMP-dependent protein kinase catalytic subunit beta
TaxID9606
Evidenceevidence at protein level
Length351
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesPRKACB

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0001843 neural tube closure
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002250 adaptive immune response
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003091 renal water homeostasis
GO:0004679 AMP-activated protein kinase activity
GO:0004691 cAMP-dependent protein kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005952 cAMP-dependent protein kinase complex
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007596 blood coagulation
GO:0010737 protein kinase A signaling
GO:0031625 ubiquitin protein ligase binding
GO:0034199 activation of protein kinase A activity
GO:0034380 high-density lipoprotein particle assembly
GO:0045202 synapse
GO:0048471 perinuclear region of cytoplasm
GO:0051447 negative regulation of meiotic cell cycle
GO:0070062 extracellular exosome
GO:0070613 regulation of protein processing
GO:0071377 cellular response to glucagon stimulus
GO:0097338 response to clozapine
GO:0097546 ciliary base
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR044109 cAMP-dependent protein kinase catalytic subunitFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB02482 PhosphonothreonineDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink