Entity Details

Primary name HEMH_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22830
EntryNameHEMH_HUMAN
FullNameFerrochelatase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length423
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesFECH

GO terms

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GOName
GO:0004325 ferrochelatase activity
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0006091 generation of precursor metabolites and energy
GO:0006783 heme biosynthetic process
GO:0008198 ferrous iron binding
GO:0009416 response to light stimulus
GO:0010288 response to lead ion
GO:0017085 response to insecticide
GO:0042493 response to drug
GO:0045471 response to ethanol
GO:0046501 protoporphyrinogen IX metabolic process
GO:0046685 response to arsenic-containing substance
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0051597 response to methylmercury
GO:0070541 response to platinum ion
GO:0071549 cellular response to dexamethasone stimulus

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR001015 FerrochelataseFamilyFamily
IPR019772 Ferrochelatase, active siteSiteActive site
IPR033644 Ferrochelatase, C-terminalDomainDomain
IPR033659 Ferrochelatase, N-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB02659 Cholic AcidDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink