Entity Details

Primary name PTPRE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP23469
EntryNamePTPRE_HUMAN
FullNameReceptor-type tyrosine-protein phosphatase epsilon
TaxID9606
Evidenceevidence at protein level
Length700
SequenceStatuscomplete
DateCreated1991-11-01
DateModified2021-06-02

Ontological Relatives

GenesPTPRE

GO terms

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GOName
GO:0004725 protein tyrosine phosphatase activity
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006470 protein dephosphorylation
GO:0016021 integral component of membrane
GO:0046627 negative regulation of insulin receptor signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR016336 Receptor tyrosine-protein phosphatase, alpha/epsilon-typeFamilyFamily
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00630 Alendronic acidDrugbanksmall molecule
DB01133 Tiludronic acidDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PTPRE_HUMANYES_MOUSEMINT14980517 details