Entity Details

Primary name SP100_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP23497
EntryNameSP100_HUMAN
FullNameNuclear autoantigen Sp-100
TaxID9606
Evidenceevidence at protein level
Length879
SequenceStatuscomplete
DateCreated1991-11-01
DateModified2021-06-02

Ontological Relatives

GenesSP100

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000723 telomere maintenance
GO:0000781 chromosome, telomeric region
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0008134 transcription factor binding
GO:0010596 negative regulation of endothelial cell migration
GO:0016032 viral process
GO:0016604 nuclear body
GO:0016605 PML body
GO:0019900 kinase binding
GO:0019904 protein domain specific binding
GO:0032526 response to retinoic acid
GO:0032897 negative regulation of viral transcription
GO:0034097 response to cytokine
GO:0034340 response to type I interferon
GO:0034341 response to interferon-gamma
GO:0034399 nuclear periphery
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043392 negative regulation of DNA binding
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0045185 maintenance of protein location
GO:0045765 regulation of angiogenesis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046826 negative regulation of protein export from nucleus
GO:0046983 protein dimerization activity
GO:0048384 retinoic acid receptor signaling pathway
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051271 negative regulation of cellular component movement
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
GO:0070087 chromo shadow domain binding
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902044 regulation of Fas signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000770 SAND domainDomainDomain
IPR004865 HSR domainDomainDomain
IPR009071 High mobility group box domainDomainDomain
IPR010919 SAND-like domain superfamilyFamilyHomologous superfamily
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily
IPR043563 Nuclear body protein Sp110/Sp140/Sp140LFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SP100_HUMANUBC9_MOUSEBioGRID11792325 details