Entity Details

Primary name SAHH_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP23526
EntryNameSAHH_HUMAN
FullNameAdenosylhomocysteinase
TaxID9606
Evidenceevidence at protein level
Length432
SequenceStatuscomplete
DateCreated1991-11-01
DateModified2021-06-02

Ontological Relatives

GenesAHCY

GO terms

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GOName
GO:0000096 sulfur amino acid metabolic process
GO:0001666 response to hypoxia
GO:0002439 chronic inflammatory response to antigenic stimulus
GO:0004013 adenosylhomocysteinase activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006730 one-carbon metabolic process
GO:0007584 response to nutrient
GO:0019510 S-adenosylhomocysteine catabolic process
GO:0030554 adenyl nucleotide binding
GO:0032259 methylation
GO:0033353 S-adenosylmethionine cycle
GO:0042470 melanosome
GO:0042745 circadian sleep/wake cycle
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0051287 NAD binding
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm
Melanosome

Domains

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DomainNameCategoryType
IPR000043 Adenosylhomocysteinase-likeFamilyFamily
IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domainDomainDomain
IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved siteSiteConserved site
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR042172 Adenosylhomocysteinase-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB03216 (1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)AdenineDrugbanksmall molecule
DB03273 3'-Oxo-AdenosineDrugbanksmall molecule
DB03769 D-EritadenineDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SAHH_HUMANMK13_MOUSEBioGRID19135240 details