Entity Details - PICKLE: A Protein InteraCtion KnowLedgebasE

Genes

CFL1

Show/Hide Table

GO	Name
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005925	focal adhesion
GO:0007010	cytoskeleton organization
GO:0007266	Rho protein signal transduction
GO:0009615	response to virus
GO:0015629	actin cytoskeleton
GO:0016020	membrane
GO:0016032	viral process
GO:0016363	nuclear matrix
GO:0022604	regulation of cell morphogenesis
GO:0030027	lamellipodium
GO:0030036	actin cytoskeleton organization
GO:0030042	actin filament depolymerization
GO:0030043	actin filament fragmentation
GO:0031258	lamellipodium membrane
GO:0031982	vesicle
GO:0032587	ruffle membrane
GO:0035722	interleukin-12-mediated signaling pathway
GO:0040019	positive regulation of embryonic development
GO:0043066	negative regulation of apoptotic process
GO:0044794	positive regulation by host of viral process
GO:0048870	cell motility
GO:0051014	actin filament severing
GO:0051015	actin filament binding
GO:0051293	establishment of spindle localization
GO:0061001	regulation of dendritic spine morphogenesis
GO:0070062	extracellular exosome

Show/Hide Table

Show/Hide Table

Domain	Name	Category	Type
IPR002108	Actin-depolymerising factor homology domain	Domain	Domain
IPR017904	ADF/Cofilin	Family	Family
IPR027234	Cofilin 1	Family	Family
IPR029006	ADF-H/Gelsolin-like domain superfamily	Family	Homologous superfamily

Show/Hide Table

Show/Hide Table

Drug	Name	Source	Type
DB04147	Dodecyldimethylamine N-oxide	Drugbank	small molecule
DB09130	Copper	Drugbank	small molecule
DB11638	Artenimol	Drugbank	small molecule

1 interaction

Interactor	Partner	Sources	Publications	Link
COF1_HUMAN	DNM1L_MOUSE	MINT	31063459	details