Entity Details

Primary name RC3H2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP0C090
EntryNameRC3H2_MOUSE
FullNameRoquin-2
TaxID10090
Evidenceevidence at protein level
Length1187
SequenceStatuscomplete
DateCreated2005-08-16
DateModified2021-06-02

Ontological Relatives

GenesRc3h2

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000932 P-body
GO:0001782 B cell homeostasis
GO:0003677 DNA binding
GO:0003725 double-stranded RNA binding
GO:0003729 mRNA binding
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0009791 post-embryonic development
GO:0009986 cell surface
GO:0010468 regulation of gene expression
GO:0010494 cytoplasmic stress granule
GO:0010608 posttranscriptional regulation of gene expression
GO:0016020 membrane
GO:0035264 multicellular organism growth
GO:0035613 RNA stem-loop binding
GO:0042098 T cell proliferation
GO:0043029 T cell homeostasis
GO:0043231 intracellular membrane-bounded organelle
GO:0043488 regulation of mRNA stability
GO:0046872 metal ion binding
GO:0048286 lung alveolus development
GO:0048535 lymph node development
GO:0048536 spleen development
GO:0050852 T cell receptor signaling pathway
GO:0060173 limb development
GO:0061470 T follicular helper cell differentiation
GO:0061630 ubiquitin protein ligase activity
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:2000320 negative regulation of T-helper 17 cell differentiation
GO:2000628 regulation of miRNA metabolic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000571 Zinc finger, CCCH-typeDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR027370 RING-type zinc-finger, LisH dimerisation motifDomainDomain
IPR032670 Roquin-2FamilyFamily
IPR036855 Zinc finger, CCCH-type superfamilyFamilyHomologous superfamily
IPR041523 Roquin IIDomainDomain

Diseases

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Interactions

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