Entity Details

Primary name TNR6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP25445
EntryNameTNR6_HUMAN
FullNameTumor necrosis factor receptor superfamily member 6
TaxID9606
Evidenceevidence at protein level
Length335
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesFAS

GO terms

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GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0005031 tumor necrosis factor-activated receptor activity
GO:0005516 calmodulin binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006924 activation-induced cell death of T cells
GO:0006955 immune response
GO:0007165 signal transduction
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016604 nuclear body
GO:0019900 kinase binding
GO:0031264 death-inducing signaling complex
GO:0031265 CD95 death-inducing signaling complex
GO:0032872 regulation of stress-activated MAPK cascade
GO:0034198 cellular response to amino acid starvation
GO:0036337 Fas signaling pathway
GO:0038023 signaling receptor activity
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0045121 membrane raft
GO:0065003 protein-containing complex assembly
GO:0070062 extracellular exosome
GO:0071260 cellular response to mechanical stimulus
GO:0071455 cellular response to hyperoxia
GO:0097049 motor neuron apoptotic process
GO:0097190 apoptotic signaling pathway
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097527 necroptotic signaling pathway
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001235 positive regulation of apoptotic signaling pathway
GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Membrane raft
Secreted

Domains

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DomainNameCategoryType
IPR000488 Death domainDomainDomain
IPR001368 TNFR/NGFR cysteine-rich regionDomainDomain
IPR008063 Fas receptorFamilyFamily
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR033998 Fas receptor, death domainDomainDomain
IPR033999 Fas receptor, N-terminalDomainDomain

Diseases

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