Entity Details

Primary name DDX6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP26196
EntryNameDDX6_HUMAN
FullNameProbable ATP-dependent RNA helicase DDX6
TaxID9606
Evidenceevidence at protein level
Length483
SequenceStatuscomplete
DateCreated1992-05-01
DateModified2021-06-02

Ontological Relatives

GenesDDX6

GO terms

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GOName
GO:0000792 heterochromatin
GO:0000932 P-body
GO:0001520 outer dense fiber
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0003729 mRNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005912 adherens junction
GO:0010494 cytoplasmic stress granule
GO:0016020 membrane
GO:0016442 RISC complex
GO:0017148 negative regulation of translation
GO:0019074 viral RNA genome packaging
GO:0019827 stem cell population maintenance
GO:0019904 protein domain specific binding
GO:0033391 chromatoid body
GO:0033962 P-body assembly
GO:0034063 stress granule assembly
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0043928 exonucleolytic catabolism of deadenylated mRNA
GO:0045296 cadherin binding
GO:0045665 negative regulation of neuron differentiation
GO:0048471 perinuclear region of cytoplasm
GO:0048515 spermatid differentiation
GO:0061830 concave side of sperm head
GO:0097227 sperm annulus
GO:1905618 positive regulation of miRNA mediated inhibition of translation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000629 ATP-dependent RNA helicase DEAD-box, conserved siteSiteConserved site
IPR001650 Helicase, C-terminalDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR014014 RNA helicase, DEAD-box type, Q motifDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01694 D-tartaric acidDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DDX6_HUMANRC3H1_MOUSEInnateDB20639877 details