Entity Details

Primary name U2AF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP26368
EntryNameU2AF2_HUMAN
FullNameSplicing factor U2AF 65 kDa subunit
TaxID9606
Evidenceevidence at protein level
Length475
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesU2AF2

GO terms

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GOName
GO:0000243 commitment complex
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0006397 mRNA processing
GO:0006405 RNA export from nucleus
GO:0006406 mRNA export from nucleus
GO:0008187 poly-pyrimidine tract binding
GO:0016607 nuclear speck
GO:0019899 enzyme binding
GO:0030628 pre-mRNA 3'-splice site binding
GO:0031124 mRNA 3'-end processing
GO:0031397 negative regulation of protein ubiquitination
GO:0033120 positive regulation of RNA splicing
GO:0048025 negative regulation of mRNA splicing, via spliceosome
GO:0070742 C2H2 zinc finger domain binding
GO:0071004 U2-type prespliceosome
GO:0089701 U2AF complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR006529 U2 snRNP auxilliary factor, large subunit, splicing factorFamilyFamily
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink