Entity Details

Primary name AMPL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP28838
EntryNameAMPL_HUMAN
FullNameCytosol aminopeptidase
TaxID9606
Evidenceevidence at protein level
Length519
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesLAP3

GO terms

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GOName
GO:0004177 aminopeptidase activity
GO:0004180 carboxypeptidase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0006508 proteolysis
GO:0008235 metalloexopeptidase activity
GO:0030145 manganese ion binding
GO:0030496 midbody
GO:0070006 metalloaminopeptidase activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminalDomainDomain
IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminalDomainDomain
IPR011356 Peptidase M17, leucine aminopeptidase/peptidase BFamilyFamily
IPR023042 Peptidase M17, leucine aminopeptidaseFamilyFamily
IPR043472 Macro domain-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02386 Leucine Phosphonic AcidDrugbanksmall molecule
DB07448 (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acidDrugbanksmall molecule
DB08766 ZofenoprilatDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
AMPL_HUMANTPPC2_MOUSEMINT21827752 details