Entity Details

Primary name TKT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP29401
EntryNameTKT_HUMAN
FullNameTransketolase
TaxID9606
Evidenceevidence at protein level
Length623
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesTKT

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004802 transketolase activity
GO:0005509 calcium ion binding
GO:0005654 nucleoplasm
GO:0005777 peroxisome
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005999 xylulose biosynthetic process
GO:0006098 pentose-phosphate shunt
GO:0009052 pentose-phosphate shunt, non-oxidative branch
GO:0016604 nuclear body
GO:0030976 thiamine pyrophosphate binding
GO:0031982 vesicle
GO:0040008 regulation of growth
GO:0042803 protein homodimerization activity
GO:0046166 glyceraldehyde-3-phosphate biosynthetic process
GO:0046390 ribose phosphate biosynthetic process
GO:0070062 extracellular exosome

Subcellular Location

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Domains

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DomainNameCategoryType
IPR005474 Transketolase, N-terminalDomainDomain
IPR005475 Transketolase-like, pyrimidine-binding domainDomainDomain
IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain IIFamilyHomologous superfamily
IPR020826 Transketolase binding siteSiteBinding site
IPR029061 Thiamin diphosphate-binding foldFamilyHomologous superfamily
IPR033248 Transketolase, C-terminal domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB09130 CopperDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink