Entity Details

Primary name PDIA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30101
EntryNamePDIA3_HUMAN
FullNameProtein disulfide-isomerase A3
TaxID9606
Evidenceevidence at protein level
Length505
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesPDIA3

GO terms

Show/Hide Table
GOName
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0003723 RNA binding
GO:0003756 protein disulfide isomerase activity
GO:0004197 cysteine-type endopeptidase activity
GO:0004629 phospholipase C activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005925 focal adhesion
GO:0006457 protein folding
GO:0009986 cell surface
GO:0015036 disulfide oxidoreductase activity
GO:0034975 protein folding in endoplasmic reticulum
GO:0034976 response to endoplasmic reticulum stress
GO:0042470 melanosome
GO:0042802 identical protein binding
GO:0042824 MHC class I peptide loading complex
GO:0045335 phagocytic vesicle
GO:0055038 recycling endosome membrane
GO:0070062 extracellular exosome
GO:0098761 cellular response to interleukin-7
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Endoplasmic reticulum
Endoplasmic reticulum lumen
Melanosome

Domains

Show/Hide Table
DomainNameCategoryType
IPR005788 Disulphide isomeraseDomainDomain
IPR005792 Protein disulphide isomeraseFamilyFamily
IPR013766 Thioredoxin domainDomainDomain
IPR017937 Thioredoxin, conserved siteSiteConserved site
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily
IPR041868 Protein disulfide-isomerase A3, first redox inactive TRX-like domain bDomainDomain

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PDIA3_HUMANMK13_MOUSEBioGRID19135240 details