Entity Details

Primary name LRP2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionA2ARV4
EntryNameLRP2_MOUSE
FullNameLow-density lipoprotein receptor-related protein 2
TaxID10090
Evidenceevidence at protein level
Length4660
SequenceStatuscomplete
DateCreated2007-11-13
DateModified2021-06-02

Ontological Relatives

GenesLrp2

GO terms

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GOName
GO:0001822 kidney development
GO:0001843 neural tube closure
GO:0003139 secondary heart field specification
GO:0003148 outflow tract septum morphogenesis
GO:0003223 ventricular compact myocardium morphogenesis
GO:0003281 ventricular septum development
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005903 brush border
GO:0005905 clathrin-coated pit
GO:0006766 vitamin metabolic process
GO:0006897 endocytosis
GO:0006898 receptor-mediated endocytosis
GO:0007507 heart development
GO:0007605 sensory perception of sound
GO:0008283 cell population proliferation
GO:0008584 male gonad development
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010165 response to X-ray
GO:0015031 protein transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016197 endosomal transport
GO:0016324 apical plasma membrane
GO:0017124 SH3 domain binding
GO:0020028 endocytic hemoglobin import into cell
GO:0030001 metal ion transport
GO:0030139 endocytic vesicle
GO:0030165 PDZ domain binding
GO:0030424 axon
GO:0030425 dendrite
GO:0030492 hemoglobin binding
GO:0030514 negative regulation of BMP signaling pathway
GO:0030900 forebrain development
GO:0031526 brush border membrane
GO:0031904 endosome lumen
GO:0031994 insulin-like growth factor I binding
GO:0032991 protein-containing complex
GO:0035904 aorta development
GO:0042562 hormone binding
GO:0043066 negative regulation of apoptotic process
GO:0043235 receptor complex
GO:0044295 axonal growth cone
GO:0044321 response to leptin
GO:0044877 protein-containing complex binding
GO:0045056 transcytosis
GO:0045121 membrane raft
GO:0045177 apical part of cell
GO:0045807 positive regulation of endocytosis
GO:0046879 hormone secretion
GO:0050750 low-density lipoprotein particle receptor binding
GO:0050769 positive regulation of neurogenesis
GO:0051087 chaperone binding
GO:0051897 positive regulation of protein kinase B signaling
GO:0060068 vagina development
GO:0060976 coronary vasculature development
GO:0060982 coronary artery morphogenesis
GO:0061156 pulmonary artery morphogenesis
GO:0061642 chemoattraction of axon
GO:0070447 positive regulation of oligodendrocyte progenitor proliferation
GO:0071363 cellular response to growth factor stimulus
GO:0097242 amyloid-beta clearance
GO:0140058 neuron projection arborization
GO:0140077 positive regulation of lipoprotein transport
GO:0140318 protein transporter activity
GO:1904447 folate import across plasma membrane

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell projection
Endosome lumen
Membrane

Domains

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DomainNameCategoryType
IPR000033 LDLR class B repeatRepeatRepeat
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000742 EGF-like domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR011042 Six-bladed beta-propeller, TolB-likeFamilyHomologous superfamily
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved siteSiteConserved site
IPR026823 Complement Clr-like EGF domainDomainDomain
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily

Diseases

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