Entity Details

Primary name METK2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP31153
EntryNameMETK2_HUMAN
FullNameS-adenosylmethionine synthase isoform type-2
TaxID9606
Evidenceevidence at protein level
Length395
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesMAT2A

GO terms

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GOName
GO:0004478 methionine adenosyltransferase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006556 S-adenosylmethionine biosynthetic process
GO:0006730 one-carbon metabolic process
GO:0032259 methylation
GO:0034214 protein hexamerization
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0048269 methionine adenosyltransferase complex
GO:0051291 protein heterooligomerization
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Domains

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DomainNameCategoryType
IPR002133 S-adenosylmethionine synthetaseFamilyFamily
IPR022628 S-adenosylmethionine synthetase, N-terminalDomainDomain
IPR022629 S-adenosylmethionine synthetase, central domainDomainDomain
IPR022630 S-adenosylmethionine synthetase, C-terminalDomainDomain
IPR022631 S-adenosylmethionine synthetase, conserved siteSiteConserved site
IPR022636 S-adenosylmethionine synthetase superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00118 AdemetionineDrugbanksmall molecule
DB00134 MethionineDrugbanksmall molecule

Interactions

0 interactions

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