Entity Details

Primary name TIA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP31483
EntryNameTIA1_HUMAN
FullNameNucleolysin TIA-1 isoform p40
TaxID9606
Evidenceevidence at protein level
Length386
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesTIA1

GO terms

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GOName
GO:0001818 negative regulation of cytokine production
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0008143 poly(A) binding
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010494 cytoplasmic stress granule
GO:0017148 negative regulation of translation
GO:0035925 mRNA 3'-UTR AU-rich region binding
GO:0048024 regulation of mRNA splicing, via spliceosome
GO:0097165 nuclear stress granule
GO:1903608 protein localization to cytoplasmic stress granule
GO:1904037 positive regulation of epithelial cell apoptotic process
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR003954 RNA recognition motif domain, eukaryoteDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034830 TIA-1, RNA recognition motif 2DomainDomain
IPR034832 TIA-1, RNA recognition motif 3DomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TIA1_HUMANRC3H1_MOUSEBioGRID, MINT20412057 details