Entity Details

Primary name PROF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35080
EntryNamePROF2_HUMAN
FullNameProfilin-2
TaxID9606
Evidenceevidence at protein level
Length140
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesPFN2

GO terms

Show/Hide Table
GOName
GO:0003779 actin binding
GO:0003785 actin monomer binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0010633 negative regulation of epithelial cell migration
GO:0016887 ATP hydrolysis activity
GO:0030036 actin cytoskeleton organization
GO:0030833 regulation of actin filament polymerization
GO:0030837 negative regulation of actin filament polymerization
GO:0030838 positive regulation of actin filament polymerization
GO:0032233 positive regulation of actin filament bundle assembly
GO:0032781 positive regulation of ATPase activity
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0050821 protein stabilization
GO:0051496 positive regulation of stress fiber assembly
GO:0070062 extracellular exosome
GO:1900028 negative regulation of ruffle assembly

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR005454 Profilin1/2/3, vertebrateFamilyFamily
IPR005455 ProfilinFamilyFamily
IPR027310 Profilin conserved siteSiteConserved site
IPR029891 Profilin-2FamilyFamily
IPR036140 Profilin superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB02078 TriglymeDrugbanksmall molecule
DB02580 PentaglymeDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PROF2_HUMANMO4L1_MOUSEBioGRID12391155 details