Entity Details

Primary name CTNA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35221
EntryNameCTNA1_HUMAN
FullNameCatenin alpha-1
TaxID9606
Evidenceevidence at protein level
Length906
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesCTNNA1

GO terms

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GOName
GO:0001541 ovarian follicle development
GO:0001669 acrosomal vesicle
GO:0003723 RNA binding
GO:0005198 structural molecule activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005915 zonula adherens
GO:0005925 focal adhesion
GO:0007015 actin filament organization
GO:0007155 cell adhesion
GO:0007163 establishment or maintenance of cell polarity
GO:0007406 negative regulation of neuroblast proliferation
GO:0007568 aging
GO:0008013 beta-catenin binding
GO:0008584 male gonad development
GO:0014704 intercalated disc
GO:0015629 actin cytoskeleton
GO:0016264 gap junction assembly
GO:0016342 catenin complex
GO:0016477 cell migration
GO:0016600 flotillin complex
GO:0017166 vinculin binding
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0031103 axon regeneration
GO:0034332 adherens junction organization
GO:0034613 cellular protein localization
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0043297 apical junction assembly
GO:0043627 response to estrogen
GO:0045295 gamma-catenin binding
GO:0045296 cadherin binding
GO:0045880 positive regulation of smoothened signaling pathway
GO:0051015 actin filament binding
GO:0051149 positive regulation of muscle cell differentiation
GO:0071681 cellular response to indole-3-methanol
GO:0090136 epithelial cell-cell adhesion
GO:0098609 cell-cell adhesion
GO:1900181 negative regulation of protein localization to nucleus
GO:2000146 negative regulation of cell motility
GO:2001045 negative regulation of integrin-mediated signaling pathway
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000633 Vinculin, conserved siteSiteConserved site
IPR001033 Alpha-cateninFamilyFamily
IPR006077 Vinculin/alpha-cateninFamilyFamily
IPR030047 Alpha E-catenin/Alpha T-cateninFamilyFamily
IPR036723 Alpha-catenin/vinculin-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CTNA1_HUMANLIMA1_MOUSEDIP18093941 details
CTNA1_HUMANCTNB1_MOUSEMINT12640114 details