Entity Details

Primary name CTNB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35222
EntryNameCTNB1_HUMAN
FullNameCatenin beta-1
TaxID9606
Evidenceevidence at protein level
Length781
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesCTNNB1

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0005938 cell cortex
GO:0007155 cell adhesion
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0016342 catenin complex
GO:0019827 stem cell population maintenance
GO:0030054 cell junction
GO:0032481 positive regulation of type I interferon production
GO:0032993 protein-DNA complex
GO:0033234 negative regulation of protein sumoylation
GO:0035315 hair cell differentiation
GO:0036023 embryonic skeletal limb joint morphogenesis
GO:0043066 negative regulation of apoptotic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process
GO:0045202 synapse
GO:0045296 cadherin binding
GO:0048145 regulation of fibroblast proliferation
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:0061549 sympathetic ganglion development
GO:0070062 extracellular exosome
GO:0070602 regulation of centromeric sister chromatid cohesion
GO:0071681 cellular response to indole-3-methanol
GO:0071944 cell periphery
GO:0072182 regulation of nephron tubule epithelial cell differentiation
GO:0098609 cell-cell adhesion
GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
GO:1990226 histone methyltransferase binding
GO:1990907 beta-catenin-TCF complex
GO:2000008 regulation of protein localization to cell surface
GO:0000791 euchromatin
GO:0001221 transcription coregulator binding
GO:0001837 epithelial to mesenchymal transition
GO:0003682 chromatin binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0016055 Wnt signaling pathway
GO:0019899 enzyme binding
GO:0032355 response to estradiol
GO:0035995 detection of muscle stretch
GO:0042995 cell projection
GO:0043525 positive regulation of neuron apoptotic process
GO:0044325 transmembrane transporter binding
GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition
GO:0045294 alpha-catenin binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0050767 regulation of neurogenesis
GO:0070369 beta-catenin-TCF7L2 complex
GO:0071363 cellular response to growth factor stimulus
GO:1904948 midbrain dopaminergic neuron differentiation
GO:0001569 branching involved in blood vessel morphogenesis
GO:0005667 transcription regulator complex
GO:0005829 cytosol
GO:0005911 cell-cell junction
GO:0007223 Wnt signaling pathway, calcium modulating pathway
GO:0008285 negative regulation of cell population proliferation
GO:0016032 viral process
GO:0016328 lateral plasma membrane
GO:0016525 negative regulation of angiogenesis
GO:0019900 kinase binding
GO:0019903 protein phosphatase binding
GO:0030331 estrogen receptor binding
GO:0030877 beta-catenin destruction complex
GO:0030997 regulation of centriole-centriole cohesion
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032991 protein-containing complex
GO:0034333 adherens junction assembly
GO:0035635 entry of bacterium into host cell
GO:0042493 response to drug
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045976 negative regulation of mitotic cell cycle, embryonic
GO:0048471 perinuclear region of cytoplasm
GO:0048660 regulation of smooth muscle cell proliferation
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0070411 I-SMAD binding
GO:0090279 regulation of calcium ion import
GO:0140297 DNA-binding transcription factor binding
GO:1904837 beta-catenin-TCF complex assembly
GO:1990138 neuron projection extension
GO:0000209 protein polyubiquitination
GO:0000922 spindle pole
GO:0002052 positive regulation of neuroblast proliferation
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0008022 protein C-terminus binding
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process
GO:0016323 basolateral plasma membrane
GO:0034394 protein localization to cell surface
GO:0043065 positive regulation of apoptotic process
GO:0045765 regulation of angiogenesis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046332 SMAD binding
GO:0051149 positive regulation of muscle cell differentiation
GO:0051973 positive regulation of telomerase activity
GO:0060070 canonical Wnt signaling pathway
GO:0060828 regulation of canonical Wnt signaling pathway
GO:0061154 endothelial tube morphogenesis
GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation
GO:1904886 beta-catenin destruction complex disassembly
GO:1990909 Wnt signalosome

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm
Cell membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000225 ArmadilloRepeatRepeat
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR013284 Beta-cateninFamilyFamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB03904 UreaDrugbanksmall molecule