Entity Details

Primary name SOAT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35610
EntryNameSOAT1_HUMAN
FullNameSterol O-acyltransferase 1
TaxID9606
Evidenceevidence at protein level
Length550
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesSOAT1

GO terms

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GOName
GO:0000062 fatty-acyl-CoA binding
GO:0004772 sterol O-acyltransferase activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0008203 cholesterol metabolic process
GO:0008374 O-acyltransferase activity
GO:0010742 macrophage derived foam cell differentiation
GO:0010878 cholesterol storage
GO:0015485 cholesterol binding
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0033344 cholesterol efflux
GO:0034379 very-low-density lipoprotein particle assembly
GO:0034383 low-density lipoprotein particle clearance
GO:0034435 cholesterol esterification
GO:0034736 cholesterol O-acyltransferase activity
GO:0042632 cholesterol homeostasis
GO:0042802 identical protein binding
GO:0042986 positive regulation of amyloid precursor protein biosynthetic process

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR004299 Membrane bound O-acyl transferase, MBOATFamilyFamily
IPR014371 Sterol O-acyltransferase, ACAT/DAG/ARE typesFamilyFamily
IPR030687 Sterol O-acyltransferase, metazoaFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00973 EzetimibeDrugbanksmall molecule
DB01094 HesperetinDrugbanksmall molecule
DB09539 Omega-3-acid ethyl estersDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink