Entity Details

Primary name FUS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35637
EntryNameFUS_HUMAN
FullNameRNA-binding protein FUS
TaxID9606
Evidenceevidence at protein level
Length526
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesFUS

GO terms

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GOName
GO:0000398 mRNA splicing, via spliceosome
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008380 RNA splicing
GO:0042802 identical protein binding
GO:0043484 regulation of RNA splicing
GO:0046872 metal ion binding
GO:0048255 mRNA stabilization
GO:0051260 protein homooligomerization
GO:1905168 positive regulation of double-strand break repair via homologous recombination

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR001876 Zinc finger, RanBP2-typeDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034459 RNA-binding protein FUSFamilyFamily
IPR034870 TAF15/EWS/TLS familyFamilyFamily
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily
IPR036443 Zinc finger, RanBP2-type superfamilyFamilyHomologous superfamily

Diseases

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