Entity Details

Primary name AQP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP41181
EntryNameAQP2_HUMAN
FullNameAquaporin-2
TaxID9606
Evidenceevidence at protein level
Length271
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesAQP2

GO terms

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GOName
GO:0003091 renal water homeostasis
GO:0003097 renal water transport
GO:0005372 water transmembrane transporter activity
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006833 water transport
GO:0015168 glycerol transmembrane transporter activity
GO:0015250 water channel activity
GO:0015793 glycerol transport
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0030658 transport vesicle membrane
GO:0042631 cellular response to water deprivation
GO:0048471 perinuclear region of cytoplasm
GO:0051289 protein homotetramerization
GO:0055037 recycling endosome
GO:0070062 extracellular exosome
GO:0071280 cellular response to copper ion
GO:0071288 cellular response to mercury ion
GO:0072205 metanephric collecting duct development
GO:0098576 lumenal side of membrane

Subcellular Location

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Subcellular Location
Apical cell membrane
Basolateral cell membrane
Cell membrane
Cytoplasmic vesicle membrane
Golgi apparatus

Domains

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DomainNameCategoryType
IPR000425 Major intrinsic proteinFamilyFamily
IPR022357 Major intrinsic protein, conserved siteSiteConserved site
IPR023271 Aquaporin-likeFamilyHomologous superfamily
IPR034294 Aquaporin transporterFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
AQP2_HUMANNFIP1_MOUSEBioGRID28931009 details