Entity Details

Primary name CDN2A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP42771
EntryNameCDN2A_HUMAN
FullNameCyclin-dependent kinase inhibitor 2A
TaxID9606
Evidenceevidence at protein level
Length156
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesCDKN2A

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0001953 negative regulation of cell-matrix adhesion
GO:0003723 RNA binding
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007265 Ras protein signal transduction
GO:0008285 negative regulation of cell population proliferation
GO:0019901 protein kinase binding
GO:0030308 negative regulation of cell growth
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0034393 positive regulation of smooth muscle cell apoptotic process
GO:0035985 senescence-associated heterochromatin focus
GO:0035986 senescence-associated heterochromatin focus assembly
GO:0042326 negative regulation of phosphorylation
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0051059 NF-kappaB binding
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:0090398 cellular senescence
GO:0090399 replicative senescence
GO:2000111 positive regulation of macrophage apoptotic process
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle
GO:2000774 positive regulation of cellular senescence

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CDN2A_HUMANBCL6_MOUSEBioGRID15567177 details