Entity Details

Primary name MYOD1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP10085
EntryNameMYOD1_MOUSE
FullNameMyoblast determination protein 1
TaxID10090
Evidenceevidence at protein level
Length318
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesMyod1

GO terms

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GOName
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000785 chromatin
GO:0000791 euchromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007517 muscle organ development
GO:0007518 myoblast fate determination
GO:0007519 skeletal muscle tissue development
GO:0007520 myoblast fusion
GO:0008134 transcription factor binding
GO:0009267 cellular response to starvation
GO:0010468 regulation of gene expression
GO:0014902 myotube differentiation
GO:0014904 myotube cell development
GO:0014908 myotube differentiation involved in skeletal muscle regeneration
GO:0019899 enzyme binding
GO:0030016 myofibril
GO:0031490 chromatin DNA binding
GO:0031625 ubiquitin protein ligase binding
GO:0035562 negative regulation of chromatin binding
GO:0035914 skeletal muscle cell differentiation
GO:0042803 protein homodimerization activity
GO:0043403 skeletal muscle tissue regeneration
GO:0043415 positive regulation of skeletal muscle tissue regeneration
GO:0043484 regulation of RNA splicing
GO:0043503 skeletal muscle fiber adaptation
GO:0043565 sequence-specific DNA binding
GO:0043966 histone H3 acetylation
GO:0043967 histone H4 acetylation
GO:0045445 myoblast differentiation
GO:0045663 positive regulation of myoblast differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048741 skeletal muscle fiber development
GO:0048743 positive regulation of skeletal muscle fiber development
GO:0051099 positive regulation of binding
GO:0051146 striated muscle cell differentiation
GO:0051149 positive regulation of muscle cell differentiation
GO:0055007 cardiac muscle cell differentiation
GO:0070888 E-box binding
GO:0071356 cellular response to tumor necrosis factor
GO:0071385 cellular response to glucocorticoid stimulus
GO:0071392 cellular response to estradiol stimulus
GO:0071453 cellular response to oxygen levels
GO:1901741 positive regulation of myoblast fusion
GO:1905382 positive regulation of snRNA transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding
GO:2000818 negative regulation of myoblast proliferation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002546 Myogenic muscle-specific protein, N-terminalDomainDomain
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR022032 Myogenic determination factor 5DomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR039704 Myogenic factorFamilyFamily

Diseases

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Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
MYOD1_MOUSESUV91_MOUSEMINT16858404 details
MYOD1_MOUSEKAT5_HUMANMINT21936881 details
MYOD1_MOUSEID2_MOUSEBioGRID, IntAct20211142 21209940 details
MYOD1_MOUSESMAD3_MOUSEBioGRID, IntAct11711431 20211142 22036565 details
MYOD1_MOUSESMRD2_MOUSEMINT22068056 details
MYOD1_MOUSESMRD3_MOUSEMINT22068056 details
MYOD1_MOUSEMBB1A_MOUSEBioGRID, MINT22333916 details
MYOD1_MOUSEKAT2B_MOUSEBioGRID11285237 14749395 9659901 details
MYOD1_MOUSEID3_MOUSEBioGRID8759016 details
MYOD1_MOUSETRI27_MOUSEBioGRID16007160 details
MYOD1_MOUSEMYOD1_MOUSEBioGRID20211142 details
MYOD1_MOUSETFE2_MOUSEBioGRID11711431 20211142 details
MYOD1_MOUSECDK1_MOUSEBioGRID14749395 details
MYOD1_MOUSEBHE41_MOUSEBioGRID12657651 details
MYOD1_MOUSENCOA2_MOUSEBioGRID15563453 details
MYOD1_MOUSENCOA1_MOUSEBioGRID15563453 details
MYOD1_MOUSEEZH2_MOUSEBioGRID22333916 details
MYOD1_MOUSEASCL3_MOUSEBioGRID11784080 details
MYOD1_MOUSETFE2_HUMANBioGRID9050988 details
MYOD1_MOUSEMP2K1_MOUSEBioGRID21454680 details
MYOD1_MOUSECREB1_MOUSEMINT12665587 details
MYOD1_MOUSEDDX5_HUMANUniProt17011493 details
MYOD1_MOUSEDDX5_MOUSEUniProt17011493 details
MYOD1_MOUSEMYCD_MOUSEDIP17940050 details
MYOD1_MOUSEUBF1_MOUSEDIP18445650 details
MYOD1_MOUSEMEF2A_HUMANDIP7973707 details
MYOD1_MOUSEHDAC1_MOUSEBioGRID11285237 11684023 14749395 details
MYOD1_MOUSENUPR1_MOUSEBioGRID19723804 details
MYOD1_MOUSEANM5_MOUSEBioGRID17043109 details
MYOD1_MOUSEEP300_MOUSEBioGRID14749395 9659901 details
MYOD1_MOUSEKDM1A_MOUSEBioGRID20833138 details
MYOD1_MOUSEKDM1A_HUMANBioGRID20833138 details
MYOD1_MOUSET22D3_MOUSEBioGRID20124407 details
MYOD1_MOUSEFBX32_MOUSEBioGRID15531760 21454680 22673621 details
MYOD1_MOUSESMAD2_MOUSEBioGRID11711431 details
MYOD1_MOUSESMAD1_MOUSEBioGRID11711431 details
MYOD1_MOUSEPHB2_MOUSEBioGRID15173318 details