Entity Details

Primary name ANXA1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP10107
EntryNameANXA1_MOUSE
FullNameAnnexin A1
TaxID10090
Evidenceevidence at protein level
Length346
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesAnxa1

GO terms

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GOName
GO:0001533 cornified envelope
GO:0001780 neutrophil homeostasis
GO:0001891 phagocytic cup
GO:0002250 adaptive immune response
GO:0002548 monocyte chemotaxis
GO:0002685 regulation of leukocyte migration
GO:0003697 single-stranded DNA binding
GO:0003727 single-stranded RNA binding
GO:0005509 calcium ion binding
GO:0005543 phospholipid binding
GO:0005544 calcium-dependent phospholipid binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0006909 phagocytosis
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0008360 regulation of cell shape
GO:0009986 cell surface
GO:0010165 response to X-ray
GO:0014839 myoblast migration involved in skeletal muscle regeneration
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0018149 peptide cross-linking
GO:0019834 phospholipase A2 inhibitor activity
GO:0019898 extrinsic component of membrane
GO:0030073 insulin secretion
GO:0030216 keratinocyte differentiation
GO:0030659 cytoplasmic vesicle membrane
GO:0030850 prostate gland development
GO:0031018 endocrine pancreas development
GO:0031232 extrinsic component of external side of plasma membrane
GO:0031313 extrinsic component of endosome membrane
GO:0031340 positive regulation of vesicle fusion
GO:0031394 positive regulation of prostaglandin biosynthetic process
GO:0031514 motile cilium
GO:0031532 actin cytoskeleton reorganization
GO:0031901 early endosome membrane
GO:0031966 mitochondrial membrane
GO:0032355 response to estradiol
GO:0032508 DNA duplex unwinding
GO:0032652 regulation of interleukin-1 production
GO:0032717 negative regulation of interleukin-8 production
GO:0032743 positive regulation of interleukin-2 production
GO:0032991 protein-containing complex
GO:0033031 positive regulation of neutrophil apoptotic process
GO:0035924 cellular response to vascular endothelial growth factor stimulus
GO:0036121 double-stranded DNA helicase activity
GO:0042063 gliogenesis
GO:0042102 positive regulation of T cell proliferation
GO:0042127 regulation of cell population proliferation
GO:0042383 sarcolemma
GO:0042493 response to drug
GO:0042629 mast cell granule
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043434 response to peptide hormone
GO:0044849 estrous cycle
GO:0045087 innate immune response
GO:0045627 positive regulation of T-helper 1 cell differentiation
GO:0045629 negative regulation of T-helper 2 cell differentiation
GO:0045920 negative regulation of exocytosis
GO:0046632 alpha-beta T cell differentiation
GO:0046883 regulation of hormone secretion
GO:0048306 calcium-dependent protein binding
GO:0050482 arachidonic acid secretion
GO:0050709 negative regulation of protein secretion
GO:0050727 regulation of inflammatory response
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0070301 cellular response to hydrogen peroxide
GO:0070365 hepatocyte differentiation
GO:0070459 prolactin secretion
GO:0070555 response to interleukin-1
GO:0071385 cellular response to glucocorticoid stimulus
GO:0071621 granulocyte chemotaxis
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:0090303 positive regulation of wound healing
GO:0097060 synaptic membrane
GO:0097350 neutrophil clearance
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
GO:1900138 negative regulation of phospholipase A2 activity
GO:1990814 DNA/DNA annealing activity

Subcellular Location

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Subcellular Location
Apical cell membrane
Basolateral cell membrane
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic vesicle
Cytoplasmic vesicle membrane
Early endosome
Endosome membrane
Lateral cell membrane
Membrane
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR001464 AnnexinFamilyFamily
IPR002388 Annexin A1FamilyFamily
IPR018252 Annexin repeat, conserved siteSiteConserved site
IPR018502 Annexin repeatRepeatRepeat
IPR037104 Annexin superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ANXA1_MOUSEIRAK1_MOUSEIntAct15102471 details
ANXA1_MOUSEDYSF_MOUSEBioGRID, MINT14506282 details
ANXA1_MOUSEFBX32_MOUSEBioGRID22673621 details